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RCMQuest > Blog > Billing & Coding > ICD-10 > E87.1: ICD-10 Code for Hyponatremia
ICD-10

E87.1: ICD-10 Code for Hyponatremia

Alex Carter
Last updated: February 3, 2026 5:19 pm
By
Alex Carter
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ICD-10-CM Code E87.1
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Hyponatremia is a common but clinically significant electrolyte disorder that frequently impacts patient management, hospital length of stay, and reimbursement. From both a clinical and medical billing perspective, accurate ICD-10 coding is essential to reflect patient acuity, support medical necessity, and reduce denials. This guide provides a clear, coder-focused breakdown of the correct ICD-10 code for hyponatremia, related codes, documentation rules, and billing considerations—aligned with 2025 ICD-10-CM guidelines.

Contents
  • What is the ICD-10 Code for Hyponatremia?
    • When to Use E87.1
    • When Not to Use E87.1
    • Related & Alternative ICD-10 Codes
      • Common Related ICD-10 Codes
    • Documentation Rules Coders Should Verify E87.1
    • Services Commonly Supported by E87.1
        • Diagnostic & Monitoring Services
        • Procedures & Treatment
        • Follow-Up & Ongoing Care
    • Common CPT & HCPCS Code Pairings with E87.1
      • Common CPT Codes
      • Common HCPCS Codes
        • Includes
        • Excludes
      • Denial & Audit Prevention Tips
        • FAQs 
      • What is the ICD-10 code for hyponatremia? The correct ICD-10-CM code for hyponatremia is E87.1.
      • Is E87.1 a billable diagnosis code? Yes, E87.1 is a valid and billable ICD-10 code for the current fiscal year.
      • Can hyponatremia be coded as a secondary diagnosis? Yes, if it affects patient care, treatment, or monitoring.
      • Can E87.1 be used for both acute and chronic hyponatremia? Yes. ICD-10 does not differentiate between acute and chronic forms.
      • Do abnormal sodium labs automatically justify E87.1? No. Provider documentation and clinical assessment are required.

What is the ICD-10 Code for Hyponatremia?

ICD-10-CM Code: E87.1

Description: Hypo-osmolality and hyponatremia

E87.1 is the primary, billable ICD-10 code used when a provider documents hyponatremia and/or low serum osmolality that is clinically evaluated, monitored, or treated.

When to Use E87.1

Use this code when:

  • Serum sodium is documented as low (typically <135 mEq/L)
  • The provider diagnoses hyponatremia or hypo-osmolality
  • The condition impacts care decisions, treatment, or monitoring
  • Hyponatremia is a primary reason for the encounter or a clinically relevant secondary condition

It may be reported in inpatient, outpatient, and emergency settings when supported by documentation.

When Not to Use E87.1

Do not assign it when:

  • Hyponatremia is only a lab finding with no provider assessment
  • The electrolyte imbalance is inherent to a more specific, fully documented condition
  • Sodium levels are transient and not clinically addressed
  • Documentation is unclear or does not confirm hyponatremia

Coding tip: Lab values alone are insufficient. Provider interpretation is required.

Related & Alternative ICD-10 Codes

Hyponatremia often occurs secondary to other conditions. When documented, additional or alternative codes may be required.

Common Related ICD-10 Codes

  • E22.2 – Syndrome of inappropriate secretion of antidiuretic hormone (SIADH)
  • E86.0 – Dehydration
  • I50.9 – Heart failure, unspecified
  • N17.9 – Acute kidney failure, unspecified
  • K74.60 – Unspecified cirrhosis of liver
  • T50.1X5A – Adverse effect of diuretics, initial encounter

Documentation Rules Coders Should Verify E87.1

Documentation should include:

  • Provider-confirmed diagnosis of hyponatremia
  • Relevant lab results (e.g., sodium, serum osmolality)
  • Clinical significance (symptoms, monitoring, treatment)
  • Underlying cause, if known
  • Treatment plan (IV fluids, fluid restriction, medication adjustment)

Incomplete documentation is a leading cause of claim denials and audits.

Services Commonly Supported by E87.1

When medically necessary and properly documented, this ICD 10 code may support:

Diagnostic & Monitoring Services
  • Basic or comprehensive metabolic panels (BMP/CMP)
  • Serum and urine osmolality testing
  • Repeat electrolyte monitoring
Procedures & Treatment
  • IV fluid administration (normal or hypertonic saline)
  • Medication adjustments (e.g., diuretics, ADH antagonists)
  • Hospital admission or extended observation
Follow-Up & Ongoing Care
  • Inpatient E/M services
  • Outpatient follow-up visits
  • Specialist consultations (nephrology, endocrinology)

Common CPT & HCPCS Code Pairings with E87.1

While coding varies by payer and setting, this code is frequently reported with:

Common CPT Codes

  • 80048 / 80053 – Basic or comprehensive metabolic panel
  • 83930 – Blood osmolality
  • 99223–99233 – Inpatient E/M services
  • 99204–99215 – Outpatient E/M visits

Common HCPCS Codes

  • J7030 / J7040 – IV normal saline
  • J7050 – IV fluid administration
  • G2211 – Complexity add-on (when applicable)

Always confirm payer-specific coverage policies.

Includes
  • Clinically evaluated hyponatremia
  • Hypo-osmolality with documented sodium imbalance
  • Acute or chronic hyponatremia (no distinction in ICD-10)
Excludes
  • Isolated abnormal labs without provider assessment
  • Electrolyte imbalances not involving sodium
  • Conditions where hyponatremia is fully integral and not separately addressed

Denial & Audit Prevention Tips

  • Do not code hyponatremia without provider confirmation
  • Ensure treatment or monitoring is documented
  • Avoid unbundling when hyponatremia is integral to another diagnosis
  • Confirm proper sequencing with underlying conditions
  • Review annual ICD-10-CM updates for code validity

Accurate documentation and compliant coding significantly reduce audit risk.

FAQs 

What is the ICD-10 code for hyponatremia?
The correct ICD-10-CM code for hyponatremia is E87.1.

Is E87.1 a billable diagnosis code?
Yes, E87.1 is a valid and billable ICD-10 code for the current fiscal year.

Can hyponatremia be coded as a secondary diagnosis?
Yes, if it affects patient care, treatment, or monitoring.

Can E87.1 be used for both acute and chronic hyponatremia?
Yes. ICD-10 does not differentiate between acute and chronic forms.

Do abnormal sodium labs automatically justify E87.1?
No. Provider documentation and clinical assessment are required.

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ByAlex Carter
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Alex Carter is a healthcare and business content writer who turns complex medical billing topics into clear, easy-to-read content. He covers medical billing processes, coding basics, insurance workflows, compliance updates, and industry news. Alex also shares practical perspectives on billing challenges, payer changes, and real-world issues faced by providers and billing teams. When he is not writing, he stays updated on medical billing regulations, policy changes, and emerging trends shaping the healthcare revenue space.

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